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KMID : 0615720100270020105
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Jouranl of Korean Acupuncture and Moxibustion society
2010 Volume.27 No. 2 p.105 ~ p.113
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A Study on Quality Evaluation of Ojeok-san Extract Powders Distributed in Korea
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Cho Su-Won
Nam Dong-Woo
Kim Eun-Jung
Lee Seung-Deok
Kim Kap-Sung
Kim Kyung-Ho
Lee Jae-Dong
Cho Hyun-Seok
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Abstract
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Objectives : This study was performed to analyze the quality of Ojeok-san extract powders distributed in Korea.
Methods : HPLC analyses of Ojeok-san decoction produced in laboratory and 8 kinds of Ojeok-san extract powders were done. Also, quantity analyses of paeoniflorin in Paeonia lactiflora, Glycyrrhizin in Glycyrrhiza uralensis, alkaloid in Ephedra sinica, Hesperidin in Citrus unshiu Markovich, and cinnamic acid in Cinnamomum cassia Blume were performed to investigate the accurate content of 6 kinds of Ojeok-san extract powders.
Results : In the pattern analysis, the peaks were compared. The content of components in herbal extract powders was 14.7 to 15.8% of that of decoction in average. The range was measured from 8.5 to 25.7%. The pattern comparison showed significant differences among the pharmaceutical companies’ products. As for the quantity analysis, one of herbal extract powder contained insufficient amount of Paeonia lactiflora components and one of herbal extract powder was in short of Ephedra sinica components. All of the others contained more than standard component(over 90%).
Conclusions : Because herbal extract powders are also medicine, standardized manufacturing methods and consistent quality management are necessary. Therefore exaction and operation of national standards and various researches to improve the quality management of herbal extract powders is urgent.
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KEYWORD
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Ojeok-san, quality evaluation, extract powders, HPLC
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